The E-Class Sedan offers an optional Post Collision Brake, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The G80 doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The E-Class Sedan has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The G80 doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.
Both the E-Class Sedan and the G80 have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available lane departure warning systems.

